Duke researcher Dr. Adrian Hernandez is investigating common stroke medications and therapies for stroke survivors — particularly those over 65 years old, women and minorities — to help determine the benefits and risks.

His three-year study – Patient-Centered Outcomes Research into Outcomes Stroke Patients Prefer and Effectiveness Research  – will compare the effectiveness of common stroke therapies, including anticoagulants, statins and antidepressants. The research received a $2 million award from the nonprofit Patient-Centered Outcomes Research Institute this month.

Hernandez’s team will use data from the association’s Get With The Guidelines®-Stroke registry, linked with Medicare claims for long-term outcomes. The results will help inform treatment decisions through the Get With The Guidelines-Stroke program.

“We’ll look at the full range of benefits or harms of these therapies among stroke survivors,” said Adrian Hernandez, director of outcomes and faculty research of the Duke Clinical Research Institute, which will oversee the research. “Once a patient has a stroke, the major goals are recovery and prevention of another stroke. But we still don’t know a lot about the specific benefits and risks of these common therapies, especially among stroke survivors 65 years and older, women and minorities. This study aims to address these treatment gaps by partnering with stroke survivors.”

The stroke study is one of 71 projects totaling more than $114 million approved by PCORI this month.  The Institute’s mission is to fund research that will provide patients, their caregivers and clinicians with evidence-based information to make informed healthcare decisions.

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