A series of indoor cycling events hosted by CycleBar across the country on Saturday are scheduled to get people active on two wheels while raising funds to fight stroke and heart disease.

The events help kick off CycleNation, a new American Heart Association and American Stroke Association program that encourages people to ride road bikes, stationary bikes and take indoor cycling classes to improve their health.

Sponsored nationally by Amgen Cardiovascular, CycleNation and CycleBar, the effort also supports cardiovascular disease research and other community programs driving brain and heart health, according to the AHA.

For a $50 donation to the AHA/ASA, participants in Saturday’s event will peddle for 50 minutes at one of 19 CycleBar locations across the country and will be able to attend three additional CycleBar classes after the event.

According to federal physical activity guidelines, regular cycling strengthens the heart and cardiovascular system.

“Cardiovascular disease is the cause of death in roughly one in three Americans, but the risk of developing heart disease and stroke can be reduced substantially by making simple lifestyle changes,” said Mark A. Creager, M.D., immediate past president, American Heart Association/American Stroke Association in a news release. “CycleNation is making it even easier for Americans to get active and keep their heart and brain healthy.”

In October and November, CycleNation will host events in Atlanta, Cincinnati, Dallas, and Denver that will feature stationary rides at community locations, such as small music venues and sports arenas.